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Rules of Engagement: GPCRs and G Proteins

[Image: see text] G protein-coupled receptors (GPCRs) are a key drug target class. They account for over one-third of current pharmaceuticals, and both drugs that inhibit and promote receptor function are important therapeutically; in some cases, the same GPCR can be targeted with agonists and inhib...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Glukhova, Alisa, Draper-Joyce, Christopher J., Sunahara, Roger K., Christopoulos, Arthur, Wootten, Denise, Sexton, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089011/
https://ncbi.nlm.nih.gov/pubmed/32219204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00026
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