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Effects of cocaine esterase following its repeated administration with cocaine in mice

BACKGROUND: A bacterial cocaine esterase (CocE) produces robust protection and reversal of cocaine toxicity. The aim of this study was to investigate how effectiveness of CocE was changed following its repeated administration together with cocaine. METHODS: Cocaine toxicity was quantified by measuri...

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Autors principals: Ko, Mei-Chuan, Narasimhan, Diwahar, Berlin, Aaron A., Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693214/
https://ncbi.nlm.nih.gov/pubmed/19217723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2009.01.002
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