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Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine-Induced Cardiovascular Activity, and Immune Responses in Rhesus Monkeys

Previous studies have demonstrated the capacity of a long-acting mutant form of a naturally occurring bacterial double mutant cocaine esterase (DM CocE) to antagonize the reinforcing, discriminative, convulsant, and lethal effects of cocaine in rodents and reverse the increases in mean arterial pres...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Collins, Gregory T., Brim, Remy L., Noon, Kathleen R., Narasimhan, Diwahar, Lukacs, Nicholas W., Sunahara, Roger K., Woods, James H., Ko, Mei-Chuan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383034/
https://ncbi.nlm.nih.gov/pubmed/22518021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.194639
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