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Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction

Cocaine is highly addictive and there are no pharmacotherapeutic drugs available to treat acute cocaine toxicity or chronic abuse. Antagonizing an inhibitor such as cocaine using a small molecule has proven difficult. The alternative approach is to modify cocaine’s pharmacokinetic properties by sequ...

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Detalhes bibliográficos
Main Authors: Narasimhan, Diwahar, Woods, James H, Sunahara, Roger K
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290992/
https://ncbi.nlm.nih.gov/pubmed/22300094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.194
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