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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

G protein-coupled receptors (GPCRs) respond to a diverse array of ligands, mediating cellular responses to hormones and neurotransmitters, as well as the senses of smell and taste. The structures of the GPCR rhodopsin and several G proteins have been determined by x-ray crystallography, yet the orga...

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Detalles Bibliográficos
Main Authors: Whorton, Matthew R., Bokoch, Michael P., Rasmussen, Søren G. F., Huang, Bo, Zare, Richard N., Kobilka, Brian, Sunahara, Roger K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863461/
https://ncbi.nlm.nih.gov/pubmed/17452637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611448104
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