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The role of noise and positive feedback in the onset of autosomal dominant diseases

BACKGROUND: Autosomal dominant (AD) diseases result when a single mutant or non-functioning gene is present on an autosomal chromosome. These diseases often do not emerge at birth. There are presently two prevailing theories explaining the expression of AD diseases. One explanation originates from t...

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Detalhes bibliográficos
Main Authors: Bosl, William J, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902440/
https://ncbi.nlm.nih.gov/pubmed/20587063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-93
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