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1
Por Hammond, Robert G., Tan, Xuan, Chan, Matthew, Goel, Anupam, Johnson, Margaret A.
Publicado no Poly(ADP-Ribose) Polymerase (2017)
“...The macrodomains are a multifunctional protein family that function as receptors and enzymes acting...”Publicado no Poly(ADP-Ribose) Polymerase (2017)
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2
3
“... toxins using structure. We used computers to build models and analyzed each new toxin to understand...”
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4
“... group of mono-ADP-ribosyltransferase toxins along with P. aeruginosa exotoxin A and C. diphtheriae...”
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5
“... virulence factors, such as the above toxins, is a promising alternative for developing new antibiotics...”
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6
“... this applies to A(2A) adenosine receptors (ARs) and to P2Y(1) and P2Y(12) receptors (P2YRs) for ADP. These X...”
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7
Por Wei, An-Chi, Aon, Miguel A., O'Rourke, Brian, Winslow, Raimond L., Cortassa, Sonia
Publicado em 2011
“...We developed a computational model of mitochondrial energetics that includes Ca(2+), proton, Na...”Publicado em 2011
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8
Por Martinez, Betsy, Tomkins, Jeffrey, Wackett, Lawrence P., Wing, Rod, Sadowsky, Michael J.
Publicado em 2001
“... ADP was determined. Plasmid pADP-1 was previously shown to encode AtzA, AtzB, and AtzC, which catalyze...”Publicado em 2001
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9
“... sources to generate computational models. Chemical cross-linking is a technique that holds exceptional...”
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10
Por Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Publicado em 2022-01-01
Assuntos:
“...Mitochondrial ADP...”Publicado em 2022-01-01
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11
Por Puhl-Rubio, Ana C., Stashko, Michael A., Wang, Huanchen, Hardy, P. Brian, Tyagi, Vikas, Li, Bing, Wang, Xiaodong, Kireev, Dmitri, Jessen, Henning J., Frye, Stephen V., Shears, Stephen B., Pearce, Kenneth H.
Publicado no SLAS Discov (2018)
“... activities, and poor pharmacokinetic properties. Herein, we describe a new inhibitor discovery strategy...”Publicado no SLAS Discov (2018)
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12
“... the orientational disorder and the microsecond rotational motion of myosin heads. However, computer analysis...”
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13
Por Zhou, Lufang, Cortassa, Sonia, Wei, An-Chi, Aon, Miguel A., Winslow, Raimond L., O'Rourke, Brian
Publicado em 2009
“... in cardiomyocytes subjected to metabolic stress and provides a new tool for examining how alterations...”Publicado em 2009
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14
“...BACKGROUND: A computational model of myocardial energy metabolism was used to assess the metabolic...”
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15
Por Katkar, Harshwardhan H., Davtyan, Aram, Durumeric, Aleksander E.P., Hocky, Glen M., Schramm, Anthony C., De La Cruz, Enrique M., Voth, Gregory A.
Publicado no Biophys J (2018)
“... of the phosphate P(i), leaving behind a bound ADP. This subtle change in nucleotide state of actin subunits affects...”Publicado no Biophys J (2018)
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16
Por Wang, Cheng, Li, Jun-Xiong, Tang, Dang, Zhang, Jian-Qing, Fang, Li-Zhou, Fu, Wei-Ping, Liu, Ling, Dai, Lu-Ming
Publicado no Int J Chron Obstruct Pulmon Dis (2017)
“... within a biological system. Metabolic profiling of different high-resolution computed tomography (HRCT...”Publicado no Int J Chron Obstruct Pulmon Dis (2017)
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17
Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers...
Por Zoll, Joffrey, Bouitbir, Jamal, Sirvent, Pascal, Klein, Alexis, Charton, Antoine, Jimenez, Liliana, Péronnet, François R, Geny, Bernard, Richard, Ruddy
Publicado no Drug Des Devel Ther (2015)
“... in O(2) by a new electrolytic process because of O(2) trapping in water superstructures (clathrates...”Publicado no Drug Des Devel Ther (2015)
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18
Por Coleman, Robert L, Oza, Amit M, Lorusso, Domenica, Aghajanian, Carol, Oaknin, Ana, Dean, Andrew, Colombo, Nicoletta, Weberpals, Johanne I, Clamp, Andrew, Scambia, Giovanni, Leary, Alexandra, Holloway, Robert W, Gancedo, Margarita Amenedo, Fong, Peter C, Goh, Jeffrey C, O’Malley, David M, Armstrong, Deborah K, Garcia-Donas, Jesus, Swisher, Elizabeth M, Floquet, Anne, Konecny, Gottfried E, McNeish, Iain A, Scott, Clare L, Cameron, Terri, Maloney, Lara, Isaacson, Jeff, Goble, Sandra, Grace, Caroline, Harding, Thomas C, Raponi, Mitch, Sun, James, Lin, Kevin K, Giordano, Heidi, Ledermann, Jonathan A
Publicado no Lancet (2017)
“...BACKGROUND: Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity...”Publicado no Lancet (2017)
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19
“... unresolved. We compare a quantitative kinetic model of the myosin-V walk, consisting of five basic states...”
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20
Por Paijmans, Joris, Lubensky, David K., ten Wolde, Pieter Rein
Publicado no PLoS Comput Biol (2017)
“... experimental observations and building on ideas from previous mathematical models, we present a new...”Publicado no PLoS Comput Biol (2017)
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