Modeling Cardiac Action Potential Shortening Driven by Oxidative Stress-Induced Mitochondrial Oscillations in Guinea Pig Cardiomyocytes

Ischemia-induced shortening of the cardiac action potential and its heterogeneous recovery upon reperfusion are thought to set the stage for reentrant arrhythmias and sudden cardiac death. We have recently reported that the collapse of mitochondrial membrane potential (ΔΨ(m)) through a mechanism tri...

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Main Authors: Zhou, Lufang, Cortassa, Sonia, Wei, An-Chi, Aon, Miguel A., Winslow, Raimond L., O'Rourke, Brian
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2009
Ábhair:
Cellular Biophysics and Electrophysiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756351/
https://ncbi.nlm.nih.gov/pubmed/19804714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.029
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