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Modeling Cardiac Action Potential Shortening Driven by Oxidative Stress-Induced Mitochondrial Oscillations in Guinea Pig Cardiomyocytes

Ischemia-induced shortening of the cardiac action potential and its heterogeneous recovery upon reperfusion are thought to set the stage for reentrant arrhythmias and sudden cardiac death. We have recently reported that the collapse of mitochondrial membrane potential (ΔΨ(m)) through a mechanism tri...

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Detalhes bibliográficos
Main Authors: Zhou, Lufang, Cortassa, Sonia, Wei, An-Chi, Aon, Miguel A., Winslow, Raimond L., O'Rourke, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756351/
https://ncbi.nlm.nih.gov/pubmed/19804714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.029
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