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Dynamic modulation of Ca(2+) sparks by mitochondrial oscillations in isolated guinea pig cardiomyocytes under oxidative stress

Local control of Ca(2+)-induced Ca(2+) release (CICR) depends on the spatial organization of L-type Ca(2+) channels and ryanodine receptors (RyR) in the dyad. Analogously, Ca(2+) uptake by mitochondria is facilitated by their close proximity to the Ca(2+) release sites, a process required for stimul...

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Detalhes bibliográficos
Main Authors: Zhou, Lufang, Aon, Miguel A, Liu, Ting, O’Rourke, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179563/
https://ncbi.nlm.nih.gov/pubmed/21645518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.05.007
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