Impaired mitochondrial network excitability in failing guinea-pig cardiomyocytes

AIMS: Studies in guinea-pig cardiomyocytes show that reactive oxygen species (ROS) produced by a few mitochondria can propagate to their neighbours, triggering synchronized, cell-wide network oscillations via an ROS-induced ROS release (RIRR) mechanism. How mitochondria in cardiomyocytes from failin...

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Publicat a:Cardiovasc Res
Autors principals: Goh, Kah Yong, Qu, Jing, Hong, Huixian, Liu, Ting, Dell'Italia, Louis J., Wu, Yong, O'Rourke, Brian, Zhou, Lufang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692289/
https://ncbi.nlm.nih.gov/pubmed/26433944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv230
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