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Glutathione Oxidation as a Trigger of Mitochondrial Depolarization and Oscillation in Intact Hearts

Depolarization of the mitochondrial inner membrane potential (ΔΨ(m)) associated with oxidative stress is thought to be a critical factor in cardiac dysfunction and cell injury following ischemia-reperfusion or exposure to cardiotoxic agents. In isolated cardiomyocytes, mitochondrially-generated reac...

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Detalhes bibliográficos
Main Authors: Slodzinski, M.K., Aon, A.M., O’Rourke, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604133/
https://ncbi.nlm.nih.gov/pubmed/18760283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.07.017
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