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A thermodynamically consistent model of the post-translational Kai circadian clock

The principal pacemaker of the circadian clock of the cyanobacterium S. elongatus is a protein phosphorylation cycle consisting of three proteins, KaiA, KaiB and KaiC. KaiC forms a homohexamer, with each monomer consisting of two domains, CI and CII. Both domains can bind and hydrolyze ATP, but only...

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Foilsithe in:PLoS Comput Biol
Main Authors: Paijmans, Joris, Lubensky, David K., ten Wolde, Pieter Rein
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371392/
https://ncbi.nlm.nih.gov/pubmed/28296888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005415
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