Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments

Actin filaments continually assemble and disassemble within a cell. Assembled filaments “age” as a bound nucleotide ATP within each actin subunit quickly hydrolyzes followed by a slower release of the phosphate P(i), leaving behind a bound ADP. This subtle change in nucleotide state of actin subunit...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Katkar, Harshwardhan H., Davtyan, Aram, Durumeric, Aleksander E.P., Hocky, Glen M., Schramm, Anthony C., De La Cruz, Enrique M., Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Molecular Machhines, Motors, and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260209/
https://ncbi.nlm.nih.gov/pubmed/30249402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.034
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