Effects of ATP and Actin-Filament Binding on the Dynamics of the Myosin II S1 Domain

Actin and myosin interact with one another to perform a variety of cellular functions. Central to understanding the processive motion of myosin on actin is the characterization of the individual states along the mechanochemical cycle. We present an all-atom molecular dynamics simulation of the myosi...

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Bibliographic Details
Main Authors: Baker, Joseph L., Voth, Gregory A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2013
Subjects:
Molecular Machines, Motors and Nanoscale Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791303/
https://ncbi.nlm.nih.gov/pubmed/24094403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.023
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