Genome-Scale Model-Based Identification of Metabolite Indicators for Early Detection of Kidney Toxicity

Identifying early indicators of toxicant-induced organ damage is critical to provide effective treatment. To discover such indicators and the underlying mechanisms of toxicity, we used gentamicin as an exemplar kidney toxicant and performed systematic perturbation studies in Sprague Dawley rats. We...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol Sci
Egile Nagusiak: Pannala, Venkat R, Vinnakota, Kalyan C, Estes, Shanea K, Trenary, Irina, OˈBrien, Tracy P, Printz, Richard L, Papin, Jason A, Reifman, Jaques, Oyama, Tatsuya, Shiota, Masakazu, Young, Jamey D, Wallqvist, Anders
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Computational Toxicology and Databases
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000070/
https://ncbi.nlm.nih.gov/pubmed/31722432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz228
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