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Polygenic risk and pleiotropy in neurodegenerative diseases
In this paper we explore the phenomenon of pleiotropy in neurodegenerative diseases, focusing on Alzheimer's disease (AD). We summarize the various techniques developed to investigate pleiotropy among traits, elaborating in the polygenic risk scores (PRS) analysis. PRS was designed to assess a...
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| Gepubliceerd in: | Neurobiol Dis |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Academic Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378564/ https://ncbi.nlm.nih.gov/pubmed/32445791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104953 |
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