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Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
Polygenic Risk Scores (PRS) for AD offer unique possibilities for reliable identification of individuals at high and low risk of AD. However, there is little agreement in the field as to what approach should be used for genetic risk score calculations, how to model the effect of APOE, what the optim...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302739/ https://ncbi.nlm.nih.gov/pubmed/34301930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24082-z |
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