Polygenic risk and hazard scores for Alzheimer's disease prediction

OBJECTIVE: Genome‐wide association studies (GWAS) have identified over 30 susceptibility loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International Genomics of Alzheimer's Project (IGAP), Polygenic Risk Score (PRS) was successfully applied to predict life time...

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Dettagli Bibliografici
Pubblicato in:Ann Clin Transl Neurol
Autori principali: Leonenko, Ganna, Sims, Rebecca, Shoai, Maryam, Frizzati, Aura, Bossù, Paola, Spalletta, Gianfranco, Fox, Nick C., Williams, Julie, Hardy, John, Escott‐Price, Valentina
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414493/
https://ncbi.nlm.nih.gov/pubmed/30911569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.716
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