Polygenic risk and hazard scores for Alzheimer's disease prediction

OBJECTIVE: Genome‐wide association studies (GWAS) have identified over 30 susceptibility loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International Genomics of Alzheimer's Project (IGAP), Polygenic Risk Score (PRS) was successfully applied to predict life time...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Leonenko, Ganna, Sims, Rebecca, Shoai, Maryam, Frizzati, Aura, Bossù, Paola, Spalletta, Gianfranco, Fox, Nick C., Williams, Julie, Hardy, John, Escott‐Price, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414493/
https://ncbi.nlm.nih.gov/pubmed/30911569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.716
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