Genetic risk for alzheimer disease is distinct from genetic risk for amyloid deposition

OBJECTIVE: Alzheimer disease (AD) is the most common form of dementia and is responsible for a huge and growing health care burden in the developed and developing world. The polygenic risk score (PRS) approach has shown 75 to 84% prediction accuracy of identifying individuals with AD risk. METHODS:...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Ann Neurol
Main Authors: Leonenko, Ganna, Shoai, Maryam, Bellou, Eftychia, Sims, Rebecca, Williams, Julie, Hardy, John, Escott‐Price, Valentina
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771864/
https://ncbi.nlm.nih.gov/pubmed/31199530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25530
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