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Defining functional variants associated with Alzheimer’s disease in the induced immune response

Defining the mechanisms involved in the aetiology of Alzheimer’s disease from genome-wide association studies alone is challenging since Alzheimer’s disease is polygenic and most genetic variants are non-coding. Non-coding Alzheimer’s disease risk variants can influence gene expression by affecting...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Brain Commun
Hlavní autoři: Harwood, Janet C, Leonenko, Ganna, Sims, Rebecca, Escott-Price, Valentina, Williams, Julie, Holmans, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087896/
https://ncbi.nlm.nih.gov/pubmed/33959712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab083
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