Age-dependent effect of APOE and polygenic component on Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative condition with significant genetic heritability. Several genes have been implicated in the onset of AD with the apolipoprotein E (APOE) gene being the strongest single genetic risk loci. Evidence suggests that the effect of APOE alters...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Bellou, Eftychia, Baker, Emily, Leonenko, Ganna, Bracher-Smith, Matthew, Daunt, Paula, Menzies, Georgina, Williams, Julie, Escott-Price, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308803/
https://ncbi.nlm.nih.gov/pubmed/32464432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.04.024
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