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Polygenic risk and pleiotropy in neurodegenerative diseases

In this paper we explore the phenomenon of pleiotropy in neurodegenerative diseases, focusing on Alzheimer's disease (AD). We summarize the various techniques developed to investigate pleiotropy among traits, elaborating in the polygenic risk scores (PRS) analysis. PRS was designed to assess a...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Dis
Asıl Yazarlar: Bellou, Eftychia, Stevenson-Hoare, Joshua, Escott-Price, Valentina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Academic Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378564/
https://ncbi.nlm.nih.gov/pubmed/32445791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104953
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