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Polygenic Risk Score Analysis of Pathologically Confirmed Alzheimer's Disease

Previous estimates of the utility of polygenic risk score analysis for the prediction of Alzheimer's disease have given Area Under the Curve estimates of <80%. However, these have been based on the genetic analysis of clinical case control series. Here we apply the same analytic approaches t...

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Détails bibliographiques
Publié dans:Ann Neurol
Auteurs principaux: Escott-Price, Valentina, Myers, Amanda J., Huentelman, Matt, Hardy, John
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599118/
https://ncbi.nlm.nih.gov/pubmed/28727176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24999
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