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Polygenic Risk Score Analysis of Pathologically Confirmed Alzheimer's Disease

Previous estimates of the utility of polygenic risk score analysis for the prediction of Alzheimer's disease have given Area Under the Curve estimates of <80%. However, these have been based on the genetic analysis of clinical case control series. Here we apply the same analytic approaches t...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Escott-Price, Valentina, Myers, Amanda J., Huentelman, Matt, Hardy, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599118/
https://ncbi.nlm.nih.gov/pubmed/28727176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24999
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