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From Polygenic Scores to Precision Medicine in Alzheimer’s Disease: A Systematic Review
BACKGROUND: Late-onset Alzheimer’s disease (AD) is highly heritable. The effect of many common genetic variants, single nucleotide polymorphisms (SNPs), confer risk. Variants are clustered in areas of biology, notably immunity and inflammation, cholesterol metabolism, endocytosis, and ubiquitination...
में बचाया:
| में प्रकाशित: | J Alzheimers Dis |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
IOS Press
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242840/ https://ncbi.nlm.nih.gov/pubmed/32250305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191233 |
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