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From Polygenic Scores to Precision Medicine in Alzheimer’s Disease: A Systematic Review
BACKGROUND: Late-onset Alzheimer’s disease (AD) is highly heritable. The effect of many common genetic variants, single nucleotide polymorphisms (SNPs), confer risk. Variants are clustered in areas of biology, notably immunity and inflammation, cholesterol metabolism, endocytosis, and ubiquitination...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
IOS Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242840/ https://ncbi.nlm.nih.gov/pubmed/32250305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191233 |
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