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From Polygenic Scores to Precision Medicine in Alzheimer’s Disease: A Systematic Review
BACKGROUND: Late-onset Alzheimer’s disease (AD) is highly heritable. The effect of many common genetic variants, single nucleotide polymorphisms (SNPs), confer risk. Variants are clustered in areas of biology, notably immunity and inflammation, cholesterol metabolism, endocytosis, and ubiquitination...
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| Опубликовано в: : | J Alzheimers Dis |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
IOS Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242840/ https://ncbi.nlm.nih.gov/pubmed/32250305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191233 |
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