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Polygenic risk and pleiotropy in neurodegenerative diseases
In this paper we explore the phenomenon of pleiotropy in neurodegenerative diseases, focusing on Alzheimer's disease (AD). We summarize the various techniques developed to investigate pleiotropy among traits, elaborating in the polygenic risk scores (PRS) analysis. PRS was designed to assess a...
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| 出版年: | Neurobiol Dis |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Academic Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378564/ https://ncbi.nlm.nih.gov/pubmed/32445791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104953 |
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