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Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the activity of the IAV hemagglutinin (HA) attachment protein and the host sialic acid (SIA) receptor r...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Du, Wenjuan, Dai, Meiling, Li, Zeshi, Boons, Geert-Jan, Peeters, Ben, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158415/
https://ncbi.nlm.nih.gov/pubmed/30089692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-18
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