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Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the activity of the IAV hemagglutinin (HA) attachment protein and the host sialic acid (SIA) receptor r...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Du, Wenjuan, Dai, Meiling, Li, Zeshi, Boons, Geert-Jan, Peeters, Ben, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158415/
https://ncbi.nlm.nih.gov/pubmed/30089692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-18
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