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Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the activity of the IAV hemagglutinin (HA) attachment protein and the host sialic acid (SIA) receptor r...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Du, Wenjuan, Dai, Meiling, Li, Zeshi, Boons, Geert-Jan, Peeters, Ben, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158415/
https://ncbi.nlm.nih.gov/pubmed/30089692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-18
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