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Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the activity of the IAV hemagglutinin (HA) attachment protein and the host sialic acid (SIA) receptor r...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Du, Wenjuan, Dai, Meiling, Li, Zeshi, Boons, Geert-Jan, Peeters, Ben, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158415/
https://ncbi.nlm.nih.gov/pubmed/30089692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-18
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