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Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the activity of the IAV hemagglutinin (HA) attachment protein and the host sialic acid (SIA) receptor r...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Du, Wenjuan, Dai, Meiling, Li, Zeshi, Boons, Geert-Jan, Peeters, Ben, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158415/
https://ncbi.nlm.nih.gov/pubmed/30089692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01243-18
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