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Identification of Residues That Affect Oligomerization and/or Enzymatic Activity of Influenza Virus H5N1 Neuraminidase Proteins

Influenza A virus (IAV) attachment to and release from sialoside receptors is determined by the balance between hemagglutinin (HA) and neuraminidase (NA). The molecular determinants that mediate the specificity and activity of NA are still poorly understood. In this study, we aimed to design the opt...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dai, Meiling, Guo, Hongbo, Dortmans, Jos C. F. M., Dekkers, Jojanneke, Nordholm, Johan, Daniels, Robert, van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044851/
https://ncbi.nlm.nih.gov/pubmed/27512075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01346-16
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