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Polar Residues and Their Positional Context Dictate the Transmembrane Domain Interactions of Influenza A Neuraminidases

Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1–N9)...

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Bibliografiske detaljer
Main Authors: Nordholm, Johan, da Silva, Diogo V., Damjanovic, Justina, Dou, Dan, Daniels, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624445/
https://ncbi.nlm.nih.gov/pubmed/23447533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440230
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