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Polar Residues and Their Positional Context Dictate the Transmembrane Domain Interactions of Influenza A Neuraminidases

Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1–N9)...

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Autors principals: Nordholm, Johan, da Silva, Diogo V., Damjanovic, Justina, Dou, Dan, Daniels, Robert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624445/
https://ncbi.nlm.nih.gov/pubmed/23447533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440230
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