Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

Heterozygous mutations in the X-linked MECP2 gene cause the profound neurological disorder Rett syndrome (RTT)1. MeCP2 protein is an epigenetic reader whose binding to chromatin primarily depends on 5-methylcytosine (mC)2,3. Functionally, MeCP2 has been implicated in several cellular processes based...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nature
Main Authors: Tillotson, Rebekah, Selfridge, Jim, Koerner, Martha V., Gadalla, Kamal K. E., Guy, Jacky, De Sousa, Dina, Hector, Ralph D., Cobb, Stuart R., Bird, Adrian
格式: Artigo
語言:Inglês
出版: 2017
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884422/
https://ncbi.nlm.nih.gov/pubmed/29019980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24058
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍