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Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
Val-boroPro (PT-100, Talabostat) induces powerful anti-tumor immune responses in syngeneic cancer models, but its mechanism of action has not yet been established. Val-boroPro is a non-selective inhibitor of post-proline-cleaving serine proteases, and the inhibition of the highly related cytosolic s...
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| Publicado en: | Cell Chem Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856610/ https://ncbi.nlm.nih.gov/pubmed/29396289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.12.013 |
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