Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

To elucidate the involvement of individual and inter-related pathological factors [i.e., amyloid-β (Aβ), metals, and oxidative stress] in the pathogenesis of Alzheimer’s disease (AD), chemical tools have been developed. Characteristics required for such tool construction, however, have not been clea...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Lee, Hyuck Jin, Korshavn, Kyle J., Nam, Younwoo, Kang, Juhye, Paul, Thomas J., Kerr, Richard A., Youn, Il Seung, Ozbil, Mehmet, Kim, Kwang S., Ruotolo, Brandon T., Prabhakar, Rajeev, Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826595/
https://ncbi.nlm.nih.gov/pubmed/28004889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605401
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