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Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer’s disease

Chemical tools have been valuable for establishing a better understanding of the relationships between metal ion dyshomeostasis, the abnormal aggregation and accumulation of amyloid-β (Aβ), and oxidative stress in Alzheimer’s disease (AD). Still, very little information is available to correlate the...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Beck, Michael W., Derrick, Jeffrey S., Suh, Jong-Min, Kim, Mingeun, Korshavn, Kyle J., Kerr, Richard A., Cho, Woo Jong, Larsen, Scott D., Ruotolo, Brandon T., Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828035/
https://ncbi.nlm.nih.gov/pubmed/28990338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700456
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