Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer’s disease

Ítems similars

• A Small Molecule that Displays Marked Reactivity with Copper– versus Zinc–Amyloid-β Implicated in Alzheimer’s Disease
  per: Savelieff, Masha G., et al.
  Publicat: (2013)
• Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease
  per: Lee, Hyuck Jin, et al.
  Publicat: (2017)
• A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms
  per: Derrick, Jeffrey S., et al.
  Publicat: (2015)
• Amyloid-β adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation
  per: Korshavn, Kyle, et al.
  Publicat: (2016)
• Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease
  per: Beck, Michael W., et al.
  Publicat: (2016)