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Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease
The absence of effective therapeutics against Alzheimer's disease (AD) is a result of the limited understanding of its multifaceted aetiology. Because of the lack of chemical tools to identify pathological factors, investigations into AD pathogenesis have also been insubstantial. Here we report...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065625/ https://ncbi.nlm.nih.gov/pubmed/27734843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13115 |
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