The impact of standard accelerated stability conditions on antibody higher order structure as assessed by mass spectrometry

por Kerr, Richard A., Keire, David A., Ye, Hongping
Publicado en MAbs (2019)

Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-σ(K)

por Zhang, Yang, Halder, Sabyasachi, Kerr, Richard A., Parrell, Daniel, Ruotolo, Brandon, Kroos, Lee
Publicado en J Biol Chem (2016)

A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease

por Beck, Michael W., Oh, Shin Bi, Kerr, Richard A., Lee, Hyuck Jin, Kim, So Hee, Kim, Sujeong, Jang, Milim, Ruotolo, Brandon T., Lee, Joo-Yong, Lim, Mi Hee
Publicado en Chem Sci (2015)

Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer’s disease

por Beck, Michael W., Derrick, Jeffrey S., Suh, Jong-Min, Kim, Mingeun, Korshavn, Kyle J., Kerr, Richard A., Cho, Woo Jong, Larsen, Scott D., Ruotolo, Brandon T., Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Publicado en ChemMedChem (2017)

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

por Lee, Hyuck Jin, Korshavn, Kyle J., Nam, Younwoo, Kang, Juhye, Paul, Thomas J., Kerr, Richard A., Youn, Il Seung, Ozbil, Mehmet, Kim, Kwang S., Ruotolo, Brandon T., Prabhakar, Rajeev, Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Publicado en Chemistry (2017)

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms

por Derrick, Jeffrey S., Kerr, Richard A., Nam, Younwoo, Oh, Shin Bi, Lee, Hyuck Jin, Earnest, Kaylin G., Suh, Nayoung, Peck, Kristy L., Ozbil, Mehmet, Korshavn, Kyle J., Ramamoorthy, Ayyalusamy, Prabhakar, Rajeev, Merino, Edward J., Shearer, Jason, Lee, Joo-Yong, Ruotolo, Brandon T., Lim, Mi Hee
Publicado en J Am Chem Soc (2015)

Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease

por Beck, Michael W., Derrick, Jeffrey S., Kerr, Richard A., Oh, Shin Bi, Cho, Woo Jong, Lee, Shin Jung C., Ji, Yonghwan, Han, Jiyeon, Tehrani, Zahra Aliakbar, Suh, Nayoung, Kim, Sujeong, Larsen, Scott D., Kim, Kwang S., Lee, Joo-Yong, Ruotolo, Brandon T., Lim, Mi Hee
Publicado en Nat Commun (2016)