NMR profiling of biomolecules at natural abundance using 2D (1)H–(15)N and (1)H–(13)C multiplicity-separated (MS) HSQC spectra

gan Chen, Kang, Freedberg, Darón I., Keire, David A.
Cyhoeddwyd yn J Magn Reson (2014)

Comparison of NMR and Dynamic Light Scattering for Measuring Diffusion Coefficients of Formulated Insulin: Implications for Particle Size Distribution Measurements in Drug Products

gan Patil, Sharadrao M., Keire, David A., Chen, Kang
Cyhoeddwyd yn AAPS J (2017)

The impact of standard accelerated stability conditions on antibody higher order structure as assessed by mass spectrometry

gan Kerr, Richard A., Keire, David A., Ye, Hongping
Cyhoeddwyd yn MAbs (2019)

Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides

gan Hsieh, Po-Hung, Xu, Yongmei, Keire, David A, Liu, Jian
Cyhoeddwyd 2014

Chemical Structure and Composition of Major Glycans Covalently Linked to Therapeutic Monoclonal Antibodies by Middle-Down Nuclear Magnetic Resonance

gan Peng, Jiangnan, Patil, Sharadrao M., Keire, David A., Chen, Kang
Cyhoeddwyd yn Anal Chem (2018)

Editorial: Heparin and Related Polysaccharides

gan Gray, Elaine, Keire, David A., Mulloy, Barbara, Rudd, Timothy R.
Cyhoeddwyd yn Front Med (Lausanne) (2020)

Development of methods for data quantitation of spiked salmon host cell DNA in protamine sulfate by qPCR

gan Sommers, Cynthia, Rosenzweig, Barry, Oum, Lida, Thompson, Karol, Keire, David A.
Cyhoeddwyd yn Data Brief (2018)

The Lipid-Associated 3D Structure of SPA, a Broad-Spectrum Neuropeptide Antagonist with Anticancer Properties

gan Keire, David A., Kumar, Mohanraja, Hu, Weidong, Sinnett-Smith, James, Rozengurt, Enrique
Cyhoeddwyd 2006

Effects of Glycine-Extended and Serine(13)-Phosphorylated Forms of Peptide YY on Food Intake in Rats

gan Reidelberger, Roger, Haver, Alvin, Chelikani, Prasanth, Keire, David A., Reeve, Joseph R.
Cyhoeddwyd 2011

Application of Ultra-Centrifugation and Bench-Top (19)F NMR for Measuring Drug Phase Partitioning for the Ophthalmic Oil-in-Water Emulsion Products

gan Wang, Xinyi, Patil, Sharadrao M., Keire, David A., Xu, Xiaoming, Chen, Kang
Cyhoeddwyd yn AAPS PharmSciTech (2018)

Chemometric Methods to Quantify 1D and 2D NMR Spectral Differences Among Similar Protein Therapeutics

gan Chen, Kang, Park, Junyong, Li, Feng, Patil, Sharadrao M., Keire, David A.
Cyhoeddwyd yn AAPS PharmSciTech (2017)

The Micelle-Associated 3D Structures of Boc-Y(SO(3))-Nle-G-W-Nle-D-2-phenylethylester (JMV-180) and CCK-8(s) Share Conformational Elements of a Calculated CCK(1) Receptor-Bound Mod...

gan Kumar, Mohanraja, Reeve, Joseph R., Hu, Weidong, Miller, Laurence J., Keire, David A.
Cyhoeddwyd 2008

Simple NMR methods for evaluating higher order structures of monoclonal antibody therapeutics with quinary structure

gan Chen, Kang, Long, Dianna S., Lute, Scott C., Levy, Michaella J., Brorson, Kurt A., Keire, David A.
Cyhoeddwyd yn J Pharm Biomed Anal (2016)

Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin

gan Mauri, Lucio, Marinozzi, Maria, Mazzini, Giulia, Kolinski, Richard E., Karfunkle, Michael, Keire, David A., Guerrini, Marco
Cyhoeddwyd yn Molecules (2017)

A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin

gan Yang, Jingyue, Marzan, Tim Andres, Ye, Wei, Sommers, Cynthia D., Rodriguez, Jason D., Keire, David A.
Cyhoeddwyd yn AAPS J (2020)

NMR Spectroscopy for Protein Higher Order Structure Similarity Assessment in Formulated Drug Products

gan Wang, Deyun, Zhuo, You, Karfunkle, Mike, Patil, Sharadrao M., Smith, Cameron J., Keire, David A., Chen, Kang
Cyhoeddwyd yn Molecules (2021)

A Simple and Noninvasive DOSY NMR Method for Droplet Size Measurement of Intact Oil-In-Water Emulsion Drug Products

gan Patil, Sharadrao M., Li, Vincent, Peng, Jiangnan, Kozak, Darby, Xu, Jin, Cai, Bing, Keire, David A., Chen, Kang
Cyhoeddwyd yn J Pharm Sci (2018)

1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources

gan Mauri, Lucio, Marinozzi, Maria, Phatak, Nisarga, Karfunkle, Michael, St. Ange, Kalib, Guerrini, Marco, Keire, David A., Linhardt, Robert J.
Cyhoeddwyd yn Front Med (Lausanne) (2019)

PYY(1–36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass spectrometry

gan Keire, David A., Whitelegge, Julian P., Souda, Puneet, Faull, Kym F., Bassilian, Sara, Reidelberger, Roger, Haver, Alvin C., Reeve, Joseph R.
Cyhoeddwyd 2010

Precision and Robustness of 2D-NMR for structure assessment of filgrastim biosimilars

gan Ghasriani, Houman, Hodgson, Derek J., Brinson, Robert G., McEwen, Ian, Buhse, Lucinda F., Kozlowski, Steven, Marino, John P., Aubin, Yves, Keire, David A.
Cyhoeddwyd yn Nat Biotechnol (2016)