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NMR Spectroscopy for Protein Higher Order Structure Similarity Assessment in Formulated Drug Products
Peptide and protein drug molecules fold into higher order structures (HOS) in formulation and these folded structures are often critical for drug efficacy and safety. Generic or biosimilar drug products (DPs) need to show similar HOS to the reference product. The solution NMR spectroscopy is a non-i...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8307401/ https://ncbi.nlm.nih.gov/pubmed/34299526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26144251 |
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