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Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin

Because of the complexity and global nature of the heparin supply chain, the control of heparin quality during manufacturing steps is essential to ensure the safety of the final active pharmaceutical ingredient (API). For this reason, there is a need to develop consistent analytical methods able to...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mauri, Lucio, Marinozzi, Maria, Mazzini, Giulia, Kolinski, Richard E., Karfunkle, Michael, Keire, David A., Guerrini, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152302/
https://ncbi.nlm.nih.gov/pubmed/28698456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071146
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