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Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer’s Disease

To elucidate the involvement of individual and inter-related pathological factors [i.e., amyloid-β (Aβ), metals, and oxidative stress] in the pathogenesis of Alzheimer’s disease (AD), chemical tools have been developed. Characteristics required for such tool construction, however, have not been clea...

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Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: Lee, Hyuck Jin, Korshavn, Kyle J., Nam, Younwoo, Kang, Juhye, Paul, Thomas J., Kerr, Richard A., Youn, Il Seung, Ozbil, Mehmet, Kim, Kwang S., Ruotolo, Brandon T., Prabhakar, Rajeev, Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826595/
https://ncbi.nlm.nih.gov/pubmed/28004889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605401
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