An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation

Aggregates of amyloidogenic peptides are involved in the pathogenesis of several degenerative disorders. Herein, an iridium(III) complex, Ir-1, is reported as a chemical tool for oxidizing amyloidogenic peptides upon photoactivation and subsequently modulating their aggregation pathways. Ir-1 was ra...

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Publicado en:Chemistry
Main Authors: Kang, Juhye, Lee, Shin Jung C., Nam, Jung Seung, Lee, Hyuck Jin, Kang, Myeong-Gyun, Korshavn, Kyle J., Kim, Hyun-Tak, Cho, Jaeheung, Ramamoorthy, Ayyalusamy, Rhee, Hyun-Woo, Kwon, Tae-Hyuk, Lim, Mi Hee
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828235/
https://ncbi.nlm.nih.gov/pubmed/27862428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201604751
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