Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection

We compared prophylactic or continuous therapy with the investigational drug VT-1161 to that with posaconazole in treating murine mucormycosis due to Rhizopus arrhizus var. arrhizus. In the prophylaxis studies, only VT-1161 resulted in improved survival and lowered tissue fungal burden of immunosupp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Lin, Lin, Wiederhold, Nathan P., Garvey, Edward P., Hoekstra, William J., Schotzinger, Robert J., Patterson, Thomas F., Filler, Scott G., Ibrahim, Ashraf S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571349/
https://ncbi.nlm.nih.gov/pubmed/28652241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00390-17
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