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Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis

We assessed prophylactic or continuous therapy of isavuconazole, posaconazole, or voriconazole in treating pulmonary murine mucormycosis. In the prophylaxis studies, only isavuconazole treatment resulted in significantly improved survival and lowered tissue fungal burden of immunosuppressed mice inf...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Baldin, Clara, Kovanda, Laura, Wiederhold, Nathan P., Ibrahim, Ashraf S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404573/
https://ncbi.nlm.nih.gov/pubmed/28264840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02589-16
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