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Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis

We assessed prophylactic or continuous therapy of isavuconazole, posaconazole, or voriconazole in treating pulmonary murine mucormycosis. In the prophylaxis studies, only isavuconazole treatment resulted in significantly improved survival and lowered tissue fungal burden of immunosuppressed mice inf...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Baldin, Clara, Kovanda, Laura, Wiederhold, Nathan P., Ibrahim, Ashraf S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404573/
https://ncbi.nlm.nih.gov/pubmed/28264840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02589-16
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